To the Editor: The novel metallo-β-lactamase named New Delhi metallo-β-lactamase (NDM-1) was identified from Klebsiella pneumoniae and Escherichia coli ...NCBISkiptomaincontentSkiptonavigationResourcesHowToAboutNCBIAccesskeysMyNCBISignintoNCBISignOutTryoutPMCLabsandtelluswhatyouthink.LearnMore.JournalListEmergInfectDisv.18(3);2012MarPMC3309569EmergInfectDis.2012Mar;18(3):532–534.doi: 10.3201/eid1803.1103890PMCID:PMC3309569PMID:22377049NDM-1–producingKlebsiellapneumoniae,CroatiaAnnaritaMazzariol,ZrinkaBošnjak,PieroBallarini,AnaBudimir,BrankaBedenić,SmiljaKalenić,andGiuseppeCornagliaAuthorinformationArticlenotesCopyrightandLicenseinformationDisclaimerUniversityofVerona,Verona,Italy(A.Mazzariol,P.Ballarini,G.Cornaglia);UniversityofZagreb,Zagreb,Croatia(Z.Bošnjak,A.Budimir,B.Bedenić,S.Kalenić)Correspondingauthor.Addressforcorrespondence:AnnaritaMazzariol,DepartmentofPathologyandDiagnostics,UniversityofVerona,StradaLeGrazie,837134Verona,Italy;email:[email protected]:NDMmetallo-beta-lactamase,carbapenemresistance,Klebsiellapneumoniae,bacteria,CroatiaCopyrightnoticeThisarticlehasbeencitedbyotherarticlesinPMC.TotheEditor:Thenovelmetallo-β-lactamasenamedNewDelhimetallo-β-lactamase(NDM-1)wasidentifiedfromKlebsiellapneumoniaeandEscherichiacoliisolatesinSwedenfromapatientpreviouslyhospitalizedinIndia(1).NDM-1isspreadingrapidlyworldwidetononclonallyrelatedisolates,manyofwhicharedirectlyorindirectlytrackedtotheIndiansubcontinent(2).Acarbapenem-resistantK.pneumoniaestrain,KLZA,wasisolatedinMay2009fromthecultureofabloodsamplefromofa40-year-oldmanonthedayafterhisadmissiontoasurgicalintensivecareunitoftheClinicalHospitalCenterinZagreb,Croatia.Thepatienthadbeentransferredafter5daysofhospitalizationinBosniaandHerzegovinafollowingacaraccident.Theclinicalhistorymentionedantimicrobialdrugtreatmentthatdidnotincludecarbapenems(gentamicin,metronidazole,andceftriaxone)andnolinktotheIndiansubcontinent.AntimicrobialdrugsusceptibilitytestingwasperformedbyVitek2(bioMérieux,Marcy