SkipToMainContentPrescribingInformationDLBCLStagesThe4stagesofDLBCL Stagingdescribeshowfarlymphomahasspread.KeepinmindthateventhemostadvancedstagesofdiffuselargeB-celllymphoma(DLBCL)(StageIIIandStageIV)arecommonandcanbetreated.NEXT:GoalsoftreatmentImportantSafetyInformation&IndicationsBacktoTopIndicationsRITUXANHYCELA®(rituximab/hyaluronidasehuman)isaprescriptionmedicineusedtotreatadultswith:FollicularLymphoma(FL)asasingle-agenttherapyinpatientswhosediseaserecurredordidnotrespondtoinitialtreatmentFollicularLymphomaasaninitialtreatmentwithchemotherapyand,inpatientswhoseinitialtreatmentwassuccessful,asasingle-agentfollow-uptherapyFollicularLymphomaasasingleagentfollow-uptherapyforpatientswhodidnotprogressoninitialtreatmentwithCVPchemotherapyDiffuseLargeB-CellLymphoma(DLBCL)asaninitialtreatmentincombinationwithCHOPorotheranthracycline-basedchemotherapyregimensChronicLymphocyticLeukemia(CLL)incombinationwithFCchemotherapyasaninitialtreatmentorasatreatmentafterdiseasehasrecurredYoucanonlyreceiveRITUXANHYCELAafteryoureceiveatleast1fulldoseofintravenous(IV)RITUXAN®(rituximab).ReadtheIVRITUXANMedicationGuideformoreinformationaboutsevereinfusionreactions,whichusuallyhappenduringthefirstdosewithIVRITUXANRITUXANHYCELAisnotforusetotreatmedicalconditionsotherthancancersItisnotknownifRITUXANHYCELAissafeandeffectiveinchildrenWhatisthemostimportantinformationIshouldknowaboutRITUXANHYCELA?RITUXANHYCELAcancauseserioussideeffectsthatcanleadtodeath,including:Severeskinandmouthreactions:TellyourhealthcareproviderorgetmedicalhelprightawayifyougetanyofthesesymptomsatanytimeduringyourtreatmentwithRITUXANHYCELA:painfulsoresorulcersonyourskin,lips,orinyourmouth;blisters;peelingskin;rashorpustulesHepatitisBvirus(HBV)reactivation:BeforeyoureceiveRITUXANHYCELA,yourdoctorwilldobloodteststocheckforHBVinfection.IfyouhavehadhepatitisBorareacarrierofhepatitisBvirus,receivingRITUXANHYCELAcouldcausethevirustobecomeanactiveinfectionagain.HepatitisBreactivationmaycauseseriousliverproblemsincludingliverf