Systems for staging diffuse large B-cell lymphoma (DLBCL) are provided below, including the World Health Organization (WHO)/Revised European ...ForYouNews&PerspectiveDrugs&DiseasesCME&EducationAcademyVideoDecisionPointEdition:ENGLISHDEUTSCHESPAÑOLFRANÇAISPORTUGUÊSLogInSignUpIt'sFree!Edition:ENGLISHDEUTSCHESPAÑOLFRANÇAISPORTUGUÊSRegisterLogInNoResultsNoResultsForYouNews&PerspectiveDrugs&DiseasesCME&EducationAcademyVideoDecisionPointclosePleaseconfirmthatyouwouldliketologoutofMedscape.Ifyoulogout,youwillberequiredtoenteryourusernameandpasswordthenexttimeyouvisit.LogoutCancelhttps://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cDovL2VtZWRpY2luZS5tZWRzY2FwZS5jb20vYXJ0aWNsZS8yMDA3Nzg5LW92ZXJ2aWV3processing....Drugs&Diseases>OncologyDiffuseLargeB-CellLymphoma(Non-HodgkinLymphoma)Staging Updated:Dec10,2020Author:FranciscoJHernandez-Ilizaliturri,MD;ChiefEditor:MatthewCFoster,MD more...ShareEmailPrintFeedbackCloseFacebookTwitterLinkedInWhatsAppSectionsDiffuseLargeB-CellLymphoma(Non-HodgkinLymphoma)StagingSectionsDiffuseLargeB-CellLymphoma(Non-HodgkinLymphoma)StagingStagingofDiffuseLargeB-CellLymphomaQuestions&AnswersShowAllTablesReferencesStagingofDiffuseLargeB-CellLymphomaSystemsforstagingdiffuselargeB-celllymphoma(DLBCL)areprovidedbelow,includingtheWorldHealthOrganization(WHO)classification[1,2]andtheCotswoldsmodificationoftheAnnArborsystem.RiskstratificationwiththeInternationalPrognosticIndex(IPI)scoreisalsoprovided.[3]WHOclassificationDLBCL,nototherwisespecified(NOS)includesthefollowing:GerminalcenterB-celltypeActivatedB-celltypeOtherformsincludethefollowing:PrimaryDLBCLofthecentralnervoussystem(CNS)PrimarycutaneousDLBCL,legtypeEpstein-Barrvirus(EBV)–positiveDLBCLNOSDLBCLassociatedwithchronicinflammationHumanherpesvirus8(HHV8)–positiveDLBCL,NOSTable.CotswoldsmodificationofAnnArborstagingsystem(OpenTableinanewwindow)StageAreaofInvolvementISinglelymphnodegroupIIMultiplelymphnodegroupsonsamesideofdiaphragmIIMultiplelymphnodegroups