Since the first New Delhi metallo-beta-lactamase (NDM) report in 2009, NDM has spread globally causing various types of infections.NCBISkiptomaincontentSkiptonavigationResourcesHowToAboutNCBIAccesskeysMyNCBISignintoNCBISignOutTryoutPMCLabsandtelluswhatyouthink.LearnMore.JournalListInfectDrugResistv.8;2015PMC4554481InfectDrugResist.2015;8:297–309.Publishedonline2015Aug24.doi: 10.2147/IDR.S39186PMCID:PMC4554481PMID:26345624ImpactoftheNewDelhimetallo-beta-lactamaseonbeta-lactamantibioticsMonikaTZmarlicka,1MichaelDNailor,2andDavidPNicolau3MonikaTZmarlicka1DepartmentofPharmacy,HartfordHospital,Hartford,CT,USAFindarticlesbyMonikaTZmarlickaMichaelDNailor2SchoolofPharmacy,DepartmentofPharmacyPractice,UniversityofConnecticut,Storrs,CT,USAFindarticlesbyMichaelDNailorDavidPNicolau3CenterforAnti-InfectiveResearchandDevelopment,HartfordHospital,Hartford,CT,USAFindarticlesbyDavidPNicolauAuthorinformationCopyrightandLicenseinformationDisclaimer1DepartmentofPharmacy,HartfordHospital,Hartford,CT,USA2SchoolofPharmacy,DepartmentofPharmacyPractice,UniversityofConnecticut,Storrs,CT,USA3CenterforAnti-InfectiveResearchandDevelopment,HartfordHospital,Hartford,CT,USACorrespondence:DavidPNicolau,CenterforAnti-InfectiveResearchandDevelopment,HartfordHospital,80SeymourStreet,Hartford,CT06102,USA,Tel+18605453941,Fax+18609723992,[email protected]©2015Zmarlickaetal.ThisworkispublishedbyDoveMedicalPressLimited,andlicensedunderCreativeCommonsAttribution–NonCommercial(unported,v3.0)LicenseThefulltermsoftheLicenseareavailableathttp://creativecommons.org/licenses/by-nc/3.0/.Non-commercialusesoftheworkarepermittedwithoutanyfurtherpermissionfromDoveMedicalPressLimited,providedtheworkisproperlyattributed.ThisarticlehasbeencitedbyotherarticlesinPMC.SincethefirstNewDelhimetallo-beta-lactamase(NDM)reportin2009,NDMhasspreadgloballycausingvarioustypesofinfections.NDM-positiveorganismsproduceinvitroresistancephenotypestocarbapenemsandmanyotherantimicrobials.Itisthussurprisingthatthelite